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Indian J Pediatr ; 2009 May; 76(5): 547-550
Article in English | IMSEAR | ID: sea-142203

ABSTRACT

All of the cases were reevaluated with systemic and neurological examinations, serologic tests, cerebrospinal fluid investigations, magnetic resonance imaging. Age ranged between 2.5 and 16 years. Five of the cases had initial infections. Patients presented most often with motor deficits (75%), secondly with loss of consciousness (33%), and seizures (33%). Spinal fluid abnormalities occurred in 41.6%. Cranial, and spinal magnetic resonance imaging (MRI) revealed hyperintense signal changes mainly in basal ganglia and thalamus (58%), cortical and subcortical areas (33) in T2 weighted images. Myelitis was determined in two cases. Six patients were treated with steroid, and 3 were treated with intravenous immunoglobulin. Ten patients recovered completely. We observed relapse in one case and recurrence in two cases. These cases responded well to high dose intravenous prednisolone followed by oral prednisolone for 6 months.


Subject(s)
Adolescent , Adrenal Cortex Hormones/therapeutic use , Child , Child, Preschool , Cohort Studies , Diffusion Magnetic Resonance Imaging , Early Diagnosis , Encephalomyelitis, Acute Disseminated/diagnosis , Encephalomyelitis, Acute Disseminated/drug therapy , Female , Follow-Up Studies , Humans , Immunoglobulins, Intravenous/administration & dosage , Magnetic Resonance Imaging/methods , Male , Neurologic Examination/methods , Retrospective Studies , Risk Assessment , Severity of Illness Index , Spinal Puncture/methods , Treatment Outcome , Turkey
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